(2E,6E)-2,6-二甲基-2,6-辛二烯-1,8-二醇合成路线 （共 24 条）
反应条件
Gardenia jasminoides f. grandiflora cell cultures; 1.) 4 h., 2.) 7 d.; products labelled with (13)C; competition reaction; Product distributionMechanism;
参考文献
Kobayashi, Koji; Uesato, Shinichi; Ueda, Shinichi; Inouye, Hiroyuki
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 10 p. 4228 - 4234
反应条件
1: 74 percent / H2 / PtO2 / methanol / 2 h 2: 100 percent / Jones reagent / acetone View Scheme
参考文献
Nakai, Tomonori; Yajima, Arata; Akasaka, Kazuaki; Kaihoku, Takayuki; Ohtaki, Miki; Nukada, Tomoo; Ohrui, Hiroshi; Yabuta, Goro
Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 12 p. 2401 - 2408
参考文献
Williams, John R.; Lin, Charles; Chodosh, Daniel F.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5815 - 5822
反应条件
lithium aluminium tetrahydride in diethyl ether
1 h;
参考文献
Dawson, Glenn W.; Pickett, John A.; Smiley, Diane W. M.
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 3 p. 351 - 361
反应条件
tert.-butylhydroperoxide; selenium(IV) oxide in dichloromethane
T=10°C; 3 h; Yield given. Yields of byproduct given;
参考文献
Oehlschlager, Allan C.; Wong, John W.; Verigin, Victor G.; Pierce, Harold D.
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 5009 - 5017
反应条件
potassium hydroxide in methanol
0.0833333 h;
参考文献
Nakai, Tomonori; Yajima, Arata; Akasaka, Kazuaki; Kaihoku, Takayuki; Ohtaki, Miki; Nukada, Tomoo; Ohrui, Hiroshi; Yabuta, Goro
Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 12 p. 2401 - 2408
反应条件
potassium hydroxide in methanol
T=20°C; Hydrolysis;
参考文献
Aldrich, Jeffrey R.; Oliver, James E.; Waite, Geoff K.; Moore, Chris; Waters, Rolland M.
Journal of Chemical Ecology, 1996 , vol. 22, # 4 p. 729 - 738
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether
T=-15 - 0°C; 1.5 h;
参考文献
Uesato; Kobayashi; Inouye
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 3 p. 927 - 940
反应条件
1: 40 percent / SeO2, t-BuOOH / toluene / 120 h / Ambient temperature
2: 75 percent / LiAlH4 / diethyl ether / 1 h
View Scheme
参考文献
Dawson, Glenn W.; Pickett, John A.; Smiley, Diane W. M.
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 3 p. 351 - 361
反应条件
Aspergillus niger; Czepek Dox medium
T=29 - 30°C; 72 h; Yield given. Yields of byproduct given;
参考文献
Madyastha, Madhava K.; Krishna Murthy, N. S. R.
Tetrahedron Letters, 1988 , vol. 29, # 5 p. 579 - 580
