1-N-Boc-4-乙胺哌啶合成路线 （共 3 条）
反应条件
hydrogen; platinum on carbon in ethanol; water T=50°C; P=1500.15 Torr; 4 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/64221 A1, 2006 ;
Location in patent: Page/Page column 7 ;
WO 2006/064221 A1
反应条件
1: With sodium tris(acetoxy)borohydride in tetrahydrofuran T=20°C; 1 h; 2: With acetic acid in tetrahydrofuran 3: With sodium hydrogencarbonate in tetrahydrofuran; water; ethyl acetate
参考文献
AMGEN INC.
Patent: WO2007/67629 A1, 2007 ;
Location in patent: Page/Page column 65 ;
WO 2007/067629 A1
反应条件
1: With sodium cyanoborohydride; acetic acid; triethylamine in methanol T=20°C; Molecular sieves; 2: With sodium hydrogencarbonate in water
参考文献
SANOFI-AVENTIS
Patent: WO2008/77552 A1, 2008 ;
Location in patent: Page/Page column 57-58 ;
WO 2008/077552 A1
