2-甲氧基-3-甲基苯甲酸合成路线 （共 27 条）
反应条件
catalase from bovine liver in aq. phosphate buffer T=20°C; pH=7.5; 120 h; Enzymatic reaction;
参考文献
Neufeld, Katharina; Marienhagen, Jan; Schwaneberg, Ulrich; Pietruszka, Joerg
Green Chemistry, 2013 , vol. 15, # 9 p. 2408 - 2421
反应条件
niobium pentachloride in acetonitrile T=0 - 20°C; 1 h;
参考文献
Yadav; Ganganna; Bhunia, Dinesh C.; Srihari
Tetrahedron Letters, 2009 , vol. 50, # 30 p. 4318 - 4320
反应条件
1: ortho-methoxybenzoic acid With n-butyllithium; potassium tert-butylate in tetrahydrofuran T=-78°C; 2 h; 2: methyl iodide in tetrahydrofuran T=-78 - 20°C;
参考文献
Nguyen, Thi-Huu; Castanet, Anne-Sophie; Mortier, Jacques
Organic Letters, 2006 , vol. 8, # 4 p. 765 - 768
反应条件
n-butyllithium; potassium tert-butylate in tetrahydrofuran T=-78°C; 1 h;
参考文献
Nguyen, Thi-Huu; Chau, Nguyet Trang Thanh; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2007 , vol. 72, # 9 p. 3419 - 3429
反应条件
sodium hydroxide in ethanol; N,N-dimethyl-formamide
参考文献
Riker Laboratories, Inc.
Patent: US4474792 A1, 1984 ;
反应条件
1.1: potassium carbonate / acetone / 16 h / Reflux; Inert atmosphere 2.1: sodium hydroxide / methanol; water / 2 h / 20 °C / Inert atmosphere 2.2: pH 7 / Inert atmosphere View Scheme
参考文献
Neufeld, Katharina; Marienhagen, Jan; Schwaneberg, Ulrich; Pietruszka, Joerg
Green Chemistry, 2013 , vol. 15, # 9 p. 2408 - 2421
反应条件
1: iso-butyllithium; ortho-methoxybenzoic acid in tetrahydrofuran T=-65°C; 2 h; 2: methyl iodide in tetrahydrofuran T=-65 - 20°C;
参考文献
Nguyen, Thi-Huu; Castanet, Anne-Sophie; Mortier, Jacques
Organic Letters, 2006 , vol. 8, # 4 p. 765 - 768
反应条件
sodium t-butanolate 1.) THF, hexane, -75 deg C, 10 h.; Multistep reaction;
参考文献
Schlosser, Manfred; Maccaroni, Paola; Marzi, Elena
Tetrahedron, 1998 , vol. 54, # 12 p. 2763 - 2770
反应条件
1: silver nitrate 2: permanganate; acetone View Scheme
参考文献
Guillaumin
Bulletin de la Societe Chimique de France, 1910 , vol. <4> 7, p. 425
反应条件
1: mercury oxide; water containing diethyl ether; iodine 2: silver nitrate 3: permanganate; acetone View Scheme
参考文献
Guillaumin
Bulletin de la Societe Chimique de France, 1910 , vol. <4> 7, p. 425
