(R)-(-)-2-己醇合成路线 （共 34 条）
反应条件
D-glucopyranose; P450 BM3; perfluoroundecanoic acid in ethanol; N,N-dimethyl-formamide T=20°C; pH=8; 1 h; Enzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Zilly, Felipe E.; Acevedo, Juan P.; Augustyniak, Wojciech; Deege, Alfred; Reetz, Manfred T.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 12 p. 2720 - 2724
反应条件
1: 1M NaOH / lipase from Pseudomonas cepacia (SAM-I) 2: Raney-Nickel / methanol View Scheme
参考文献
Goergens, Ulrich; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1992 , vol. 3, # 9 p. 1149 - 1152
反应条件
1: 1-methyl-1-pentanol With Burkholderia cepacia lipase in isopropyl alcohol T=30°C; 0.5 h; Enzymatic reaction; 2: vinyl acetate in isopropyl alcohol T=30°C; 0.2 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ema, Tadashi; Ura, Norichika; Yoshii, Masataka; Korenaga, Toshinobu; Sakai, Takashi
Tetrahedron, 2009 , vol. 65, # 46 p. 9583 - 9591
参考文献
Fujisawa, Tamotsu; Kojima, Eiji; Itoh, Toshiyuki; Sato, Toshio
Chemistry Letters, 1985 , p. 1751 - 1754
参考文献
Goergens, Ulrich; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1992 , vol. 3, # 9 p. 1149 - 1152
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol
参考文献
Guo, Xun-Xiang; Xie, Jian-Hua; Hou, Guo-Hua; Shi, Wen-Jian; Wang, Li-Xin; Zhou, Qi-Lin
Tetrahedron Asymmetry, 2004 , vol. 15, # 14 p. 2231 - 2234
反应条件
C50H42ClN2O3Ru in 1,2-dichloro-ethane T=25°C; Molecular sieveResolution of racemate; Kinetics; enantioselective reaction;
参考文献
Mizoguchi, Hirotaka; Uchida, Tatsuya; Katsuki, Tsutomu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3178 - 3182
Angew. Chem., 2014 , vol. 126, # 12 p. 3242 - 3246,5
反应条件
1: 31 percent / H2O; ethanol / 96 h / Ambient temperature; baker's yeast (D-glucose, MgSO4) 2: 54 percent / lithium, ethylamine View Scheme
参考文献
Fujisawa, Tamotsu; Kojima, Eiji; Itoh, Toshiyuki; Sato, Toshio
Chemistry Letters, 1985 , p. 1751 - 1754
反应条件
1: 87 percent / Na2CO3, Raney-nickel / ethanol / Heating 2: 98 percent / p-TsOH, CH3OH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Noe, Christian R.; Knollmueller, M.; Dungler, K.; Miculka, C.; Gaertner, P.
Monatshefte fuer Chemie, 1991 , vol. 122, # 8 p. 705 - 718
反应条件
1: 43 percent / p-TsOH, Na2SO4 / diethyl ether / Ambient temperature 2: 87 percent / Na2CO3, Raney-nickel / ethanol / Heating 3: 98 percent / p-TsOH, CH3OH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Noe, Christian R.; Knollmueller, M.; Dungler, K.; Miculka, C.; Gaertner, P.
Monatshefte fuer Chemie, 1991 , vol. 122, # 8 p. 705 - 718
