(R)-(-)-2-己醇合成路线 （共 34 条）
反应条件
potassium phosphate; secondary alcohol dehydrogenase from Nocardia fusca AKU 2123; nicotinamide adenine dinucleotide in water T=30°C; Oxidation; pH=9.0; Enzyme kinetics;
参考文献
Li, Zhi; Buetikofer, Lukas; Witholt, Bernard
Angewandte Chemie - International Edition, 2004 , vol. 43, # 13 p. 1698 - 1702
反应条件
potassium tert-butylate; 2-(diphenylphosphino)ethylamine; (pentamethylcyclopentadienyl)Ru(1,5-cyclooctadiene)Cl in toluene T=30°C; 1 h;
参考文献
Ito, Masato; Osaku, Akihide; Kitahara, Sachiko; Hirakawa, Makoto; Ikariya, Takao
Tetrahedron Letters, 2003 , vol. 44, # 40 p. 7521 - 7523
反应条件
[Ir(η5-C5Me5)(C6H4-2-CH2NHCH3)(NCCH3)](PF6); potassium tert-butylate in toluene T=20°C; 24 h; Inert atmosphere;
参考文献
Jerphagnon, Thomas; Gayet, Arnaud J.A.; Berthiol, Florian; Ritleng, Vincent; Mrsic, Natasa; Meetsma, Auke; Pfeffer, Michel; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Chemistry - A European Journal, 2009 , vol. 15, # 46 p. 12780 - 12790
反应条件
1: 73 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / Ambient temperature 2: NH2NH2*H2O / ethanol / 0.25 h / Heating View Scheme
参考文献
Sasse, Astrid; Kiec-Kononowicz, Katarzyna; Stark, Holger; Motyl, Malgorzata; Reidemeister, Sibylle; Ganellin, C. Robin; Ligneau, Xavier; Schwartz, Jean-Charles; Schunack, Walter
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 593 - 600
