2-苄氧基阿托伐他汀-d5缩丙酮叔-丁酯合成路线 (共 2 条)
反应条件
hydrogen; acetic acid; palladium on activated charcoal in ethyl acetate Hydrogenolysis; catalytic hydrogenation;
参考文献
Chen, Bang-Chi; Sundeen, Joseph E.; Guo, Peng; Bednarz, Mark S.; Hangeland, Jon J.; Ahmed, Syed Z.; Jemal, Mohammed
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 3 p. 261 - 270
反应条件
Multi-step reaction with 2 steps 1: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating2: pivalic acid / tetrahydrofuran; toluene; heptane / Heating
参考文献
Chen, Bang-Chi; Sundeen, Joseph E.; Guo, Peng; Bednarz, Mark S.; Hangeland, Jon J.; Ahmed, Syed Z.; Jemal, Mohammed Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 3 p. 261 - 270