N-苄氧羰基-D-丙氨酸合成路线 （共 30 条）
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide; N-acetyl-L-His in water T=25°C; variation of pH, catalyst and their concentration, with an without anionic and non-ionic surfactants; Rate constantEquilibrium constant;
参考文献
Ihara, Yasuji; Hosako, Reiko; Nango, Mamoru; Kuroki, Nobuhiko
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 5 - 10
反应条件
antibody 3G2; Tris buffer; water in dimethyl sulfoxide T=25°C; Rate constant;
参考文献
Tanaka, Fujie; Kinoshita, Keiko; Tanimura, Ryuji; Fujii, Ikuo
Journal of the American Chemical Society, 1996 , vol. 118, # 10 p. 2332 - 2339
反应条件
citrate buffer; dl-cysteine hydrochloride; papain T=50°C; 24 h;
参考文献
Moriniere, Jean-Luc; Danree, Bernard; Guy, Alain
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 347 - 358
反应条件
sodium hydroxide in water T=40°C; 0.333333 h; titrisol buffer pH 8, carboxylesterase NP; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Smeets, J. W. H.; Kieboom, A. P. G.
Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, # 11 p. 490 - 495
反应条件
sodium hydrogencarbonate; sodium carbonate in water; acetonitrile T=50°C; Substitution; pH=9.5; 1 h;
参考文献
Mitulovi, Goran; Laemmerhofer, Michael; Maier; Lindner, Wolfgang
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 5 p. 449 - 461
反应条件
sodium chloride; calcium chloride; papain in N,N-dimethyl-formamide T=25°C; pH=8; 3 h; aq. bufferEnzymatic reaction;
参考文献
de Beer, Roseri J.A.C.; Zarzycka, Barbara; Amatdjais-Groenen, Helene I.V.; Jans, Sander C.B.; Nuijens, Timo; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T.
ChemBioChem, 2011 , vol. 12, # 14 p. 2201 - 2207
反应条件
toluene-4-sulfonic acid; threo-1,4-dimercapto-2,3-butanediol; papain in N,N-dimethyl-formamide pH=8; 10 h; aq. buffer;
参考文献
de Beer, Roseri J.A.C.; Zarzycka, Barbara; Mariman, Michiel; Amatdjais-Groenen, Helene I.V.; Mulders, Marc J.; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T.
ChemBioChem, 2012 , vol. 13, # 9 p. 1319 - 1326
反应条件
in various solvent(s) T=25°C; effect of the catalyst (CBZ-L-Leu-L-Hys-poly(ethyleneimine)s) on the stereoselectivity of hydrolysis; KineticsProduct distribution;
参考文献
Kimura, Yoshiharu; Kanda, Shinichi; Nango, Mamoru; Ihara, Yasuji; Koga, Joichi; et al.
Chemistry Letters, 1984 , p. 433 - 436
反应条件
ruthenium trichloride; boron trifluoride diethyl etherate; sodium carbonate; acetic acid; periodic acid; zinc 1.) toluene, -78 deg C, 30 min; 2.) water, 40 deg C, 2 h; 3.) THF, water, r.t., 12 h; 4.) CCl4, CH3CN, water, 50 deg C, 24 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Moody, Christopher J.; Lightfoot, Andrew P.; Gallagher, Peter T.
Synlett, 1997 , vol. 1997, # 6 p. 659 - 660
反应条件
sodium hydroxide; phosphate buffer; Aspergillus niger lipase; poly(vinyl alcohol) T=25°C; Yield given. Title compound not separated from byproducts;
参考文献
Miyazawa, Toshifumi; Takitani, Tadanori; Ueji, Shinichi; Yamada, Takashi; Kuwata, Shigeru
Journal of the Chemical Society, Chemical Communications, 1988 , # 17 p. 1214 - 1216
