(R)-2-乙酰基氨基-3-(2,5-二氟-苯基)-丙酸合成路线 （共 3 条）
反应条件
sodium hydroxide; Aspergillus genus acylase; sodium acetate in water T=38°C; Deacetylation; pH=8.0; 48 h;
参考文献
Tetrahedron Letters, , vol. 41, # 6 p. 923 - 927
反应条件
1: 2M NaOH / methanol; H2O / 3 h / 40 °C 2: 92 percent / p-xylene / 2 h / Heating 3: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 6 p. 923 - 927
反应条件
1: 90 percent / NaOEt / ethanol / 2 h / Heating 2: 2M NaOH / methanol; H2O / 3 h / 40 °C 3: 92 percent / p-xylene / 2 h / Heating 4: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 6 p. 923 - 927
