(2S)-2-氨基-4-甲基戊酸甲酯合成路线 （共 67 条）
反应条件
2: ethanol; NH3 View Scheme
参考文献
Journal of Biological Chemistry, , vol. 223, p. 935,945
反应条件
in dichloromethane T=20°C; 4 h;
参考文献
De Marco, Rosaria; Gioia, Maria Luisa Di; Leggio, Antonella; Liguori, Angelo; Viscomi, Maria Caterina
European Journal of Organic Chemistry, 2009 , # 22 p. 3795 - 3800
反应条件
β-cyclodextrin in water; dimethyl sulfoxide T=25°C; Rate constantMechanism;
参考文献
Barra, Monica; Rossi, Rita H. de
Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1124 - 1130
参考文献
Weygand; Geiger
Chemische Berichte, 1959 , vol. 92, p. 2099,2101
反应条件
sodium hydroxide in tetrahydrofuran
参考文献
Donkor, Isaac O.; Korukonda, Rajani; Huang, Tien L.; LeCour Jr., Louis
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 783 - 784
反应条件
1: pyridine
2: aq.-ethanolic NaOH-solution
View Scheme
参考文献
Karrer; Kehl
Helvetica Chimica Acta, 1930 , vol. 13, p. 50,54
反应条件
2: aqueous acetone; aqueous NaOH
3: palladium; aqueous HCl; acetic acid / Hydrogenation
View Scheme
参考文献
Scopes,P.M. et al.
Journal of the Chemical Society, 1965 , p. 782 - 786
反应条件
anschliessender Hydrierung an Palladium in Methanol und folgende Hydrolyse;
参考文献
Velluz et al.
Bulletin de la Societe Chimique de France, 1954 , p. 1015
反应条件
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; Inert atmosphere;
参考文献
Pan, Po-Shen; Vasko, Robert C.; Lapera, Stephanie A.; Johnson, Victoria A.; Sellers, Robert P.; Lin, Chun-Chieh; Pan, Chung-Mao; Davis, Melinda R.; Ardi, Veronica C.; McAlpine, Shelli R.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 16 p. 5806 - 5825
反应条件
triethylamine; dicyclohexyl-carbodiimide in dichloromethane
1) -5 deg C, 3 h 2) refrigerator, 48 h 3) room temperature, 4 h;
参考文献
Abou Ghalia, M. H.; Salem, Ezzeldin M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 2 p. 135 - 138
