1: With N,O-bis(trimethylsilyl) trifluoroacetamide in acetonitrile T=20°C; 0.5 h; Inert atmosphere; 2: With Au(Ph3P)+NTf2- in acetonitrile T=20°C; Inert atmosphere;
1: NaOH / dimethylformamide / 5 h / 105 °C 2: NaH / dimethylformamide / 6 h / 0 °C 3: HCl(g) / CH2Cl2 / 0.17 h / 0 - 5 °C 4: TMSBr / CH2Cl2 / 18 h / Ambient temperature View Scheme
参考文献
Brodfuehrer, Paul R.; Howell, Henry G.; Sapino, Chester Jr.; Vemishetti, Purushotham
Tetrahedron Letters, 1994 , vol. 35, # 20 p. 3243 - 3246
