6-氯-3,4-二氢-2H-1-萘酮合成路线 （共 12 条）
反应条件
hydrogenchloride; copper(l) chloride; sodium nitrite T=0 - 20°C;
参考文献
Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi
Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491
参考文献
Owton; Brunavs
Synthetic Communications, 1991 , vol. 21, # 8-9 p. 981 - 987
反应条件
hydrogenchloride; thionyl chloride; aluminium trichloride in tetrachloromethane; anhydrous dichloroethane; ethyl acetate
参考文献
E. I. Du Pont de Nemours and Company
Patent: US5474998 A1, 1995 ;
反应条件
1.1: sodium hydroxide / N,N-dimethyl acetamide / 20 °C 2.1: sodium hydroxide / 2 h / 50 - 60 °C 3.1: water / 1 h / Reflux 4.1: hydrogenchloride; sodium nitrite 4.2: 0 - 60 °C View Scheme
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
反应条件
1.1: AlCl3, aluminium chloride / toluene / 4 h / Reflux 2.1: α-bromo-α,α-dimethylacetamide; sodium hydroxide / N,N-dimethyl acetamide / 5 h / 20 °C 2.2: 1 h / 50 °C 3.1: hydrogenchloride; copper(l) chloride; sodium nitrite / 0 - 20 °C View Scheme
参考文献
Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi
Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491
反应条件
1: triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 8 h / |Inert atmosphere; |Reflux 2: CuCl2·2H2O / water; methanol / 10 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
反应条件
2: 45 percent / PPA View Scheme
参考文献
Owton; Brunavs
Synthetic Communications, 1991 , vol. 21, # 8-9 p. 981 - 987
反应条件
1.1: sodium hydroxide / 2 h / 50 - 60 °C 2.1: water / 1 h / Reflux 3.1: hydrogenchloride; sodium nitrite 3.2: 0 - 60 °C View Scheme
参考文献
Crosby, Ian T.; Shin, James K.; Capuano, Ben
Australian Journal of Chemistry, 2010 , vol. 63, # 2 p. 211 - 226
反应条件
1.1: water / 1 h / Reflux 2.1: hydrogenchloride; sodium nitrite 2.2: 0 - 60 °C View Scheme
参考文献
Crosby, Ian T.; Shin, James K.; Capuano, Ben
Australian Journal of Chemistry, 2010 , vol. 63, # 2 p. 211 - 226
反应条件
chromium(VI) oxide; acetic acid 72 h;
参考文献
Schroeter et al.
Chemische Berichte, 1930 , vol. 63, p. 1308,1325
