potassium phosphate; tetrakis(triphenylphosphine) palladium(0); triethylamine in toluene T=110°C; 72 h; Sealed tube;

1: 6-chloro-2,3-dihydroquinolin-4(1H)-one With sodium hydride in N,N-dimethyl-formamide; mineral oil T=20°C; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=80°C;

1.1: trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0 - 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 2.2: 80 °C View Scheme

1.1: sodium t-butanolate / N,N-dimethyl-formamide / 0 - 20 °C 2.1: trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0 - 20 °C 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 3.2: 80 °C View Scheme

1.1: potassium carbonate / dichloromethane / 0 - 20 °C 2.1: sodium t-butanolate / N,N-dimethyl-formamide / 0 - 20 °C 3.1: trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0 - 20 °C 4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 4.2: 80 °C View Scheme