4-(4-氯苯基)二氢呋喃-2(3H)-酮合成路线 (共 1 条)
反应条件
1: Me3SiI / CH2Cl2 / 0 deg C to r.t.
2: 95 percent / NaN3 / dimethylformamide / 75 °C
3: 95 percent / 1.) NaOH (2M); 2.) conc.HCl / Ambient temperature
4: 80 percent / 1.) H2; 2.) HCl gas / 1.) Pd-C / diethyl ether; ethanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Mazzini, Claudio; Lebreton, Jacques; Alphand, Veronique; Furstoss, Roland
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1195 - 1196