1-溴-3,4,5-三甲氧基苯合成路线 （共 68 条）
反应条件
1: With hydrogen bromide; sodium nitrite 0.5 h; 2: With copper(I) bromide in water T=20 - 100°C; Further stages.;
参考文献
Paizs, Csaba; Bartlewski-Hof, Ulrike; Retey, Janos
Chemistry - A European Journal, 2007 , vol. 13, # 10 p. 2805 - 2811
反应条件
potassium phosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane T=110°C; 18 h; Product distribution / selectivity;
参考文献
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Patent: WO2009/137322 A2, 2009 ;
Location in patent: Page/Page column 21; 22; 29; 30; 31 ;
反应条件
sodium hydroxide; dimethyl sulfate
参考文献
Scanlan, Thomas S.; Shah, Nilesh
Patent: US2003/176478 A1, 2003 ;
US 20030176478 A1
反应条件
sodium hydroxide 6 h; Heating;
参考文献
Jung, Michael E.; Lam, Patrick Yuk-Sun; Mansuri, Muzzamil M.; Speltz, Laurine M.
Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1087 - 1105
反应条件
sodium hydroxide; dimethyl sulfate in water
参考文献
The Penn State Research Foundation
Patent: US2002/128501 A1, 2002 ;
反应条件
2,2'-azo-bisisobutyronitrile; trichloromonobromomethane; Fonderma T=100°C; 0.0833333 h; Heating; Yield given. Yields of byproduct given;
参考文献
Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z.
Tetrahedron, 1987 , vol. 43, # 19 p. 4321 - 4328
反应条件
1: 1.) NaH, MeOH, 2.) N-bromosuccinimide / 1.) chloroform, 2.) -45 to -35 deg C 2: 80 percent / aq. NaOH / 6 h / Heating View Scheme
参考文献
Jung, Michael E.; Lam, Patrick Yuk-Sun; Mansuri, Muzzamil M.; Speltz, Laurine M.
Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1087 - 1105
反应条件
1: aqueous acetic acid; zinc-powder 2: aqueous alkaline solution View Scheme
参考文献
Kohn; Steiner
Journal of Organic Chemistry, 1947 , vol. 12, p. 30,32
反应条件
2,2'-azo-bisisobutyronitrile; trichloromonobromomethane; 2,2’-disulfanediyldipyridine-1-oxide 2.) 100 deg C; Yield given. Multistep reaction;
参考文献
Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z.
Tetrahedron Letters, 1985 , vol. 26, # 48 p. 5939 - 5942
反应条件
1: aq. H2O2, NaOH 2: aq. NaOH View Scheme
参考文献
Larsson,S.; Miksche,G.E.
Acta Chemica Scandinavica (1947-1973), 1972 , vol. 26, p. 2031 - 2038
