1H-吡咯并[2,3-C]吡啶-5-甲胺合成路线 (共 3 条)
反应条件
1: in N,N-dimethyl-formamide T=90°C; 2 h; 2: With hydrogenchloride; methanol; palladium on activated charcoal 16 h;
参考文献
Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798
反应条件
1.1: POBr3 / 1,1,2,2-tetrachloro-ethane / 4 h / Heating 2.1: (Ph3P)4Pd / dimethylformamide / 5 h / 80 °C 3.1: dimethylformamide / 2 h / 90 °C 3.2: MeOH; 6 M HCl / 10 percent Pd/C / 16 h View Scheme
参考文献
Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798
反应条件
1.1: (Ph3P)4Pd / dimethylformamide / 5 h / 80 °C 2.1: dimethylformamide / 2 h / 90 °C 2.2: MeOH; 6 M HCl / 10 percent Pd/C / 16 h View Scheme
参考文献
Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798