1,3,5(10)-雌二醇-3,4,17beta-三醇 4-甲醚合成路线 （共 8 条）
反应条件
copper(l) iodide; benzo-15-crown-5 in N,N-dimethyl-formamide T=105 - 110°C; 13 h;
参考文献
Chen, Shu-hua; Luo, Guan-rong; Wu, Xu-sen; Chen, Min; Zhao, Hua-ming
Steroids, 1986 , vol. 47, # 1 p. 63 - 66
反应条件
copper dichloride in methanol; N,N-dimethyl-formamide T=110°C; 0.0833333 h; Heating;
参考文献
Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao
Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715
反应条件
1: H2 / 5percent Pd/C / ethanol / Ambient temperature 2: 40 percent / NBS / dimethylformamide / 24 h / Ambient temperature 3: 75 percent / CuCl2 / methanol; dimethylformamide / 1.25 h / 110 °C / Heating View Scheme
参考文献
Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao
Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715
反应条件
1: 95 percent / NBS / dimethylformamide / 24 h / Ambient temperature 2: H2 / 5percent Pd/C / ethanol / Ambient temperature 3: 75 percent / CuCl2 / methanol; dimethylformamide / 1.25 h / 110 °C / Heating View Scheme
参考文献
Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao
Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715
反应条件
1: 50 percent / CuI / methanol; dimethylformamide 2: 80 percent / 28percent NH4OH, I2 / methanol; tetrahydrofuran / 0.5 h 3: H2 / 5percentPd/C / ethanol / Ambient temperature 4: 96 percent / CuCl2 / methanol; dimethylformamide / 0.08 h / 110 °C / Heating View Scheme
参考文献
Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao
Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715
反应条件
1: H2 / 5percentPd/C / ethanol / Ambient temperature 2: 96 percent / CuCl2 / methanol; dimethylformamide / 0.08 h / 110 °C / Heating View Scheme
参考文献
Numazawa, Mitsuteri; Ogura, Yuko; Kimura, Katsuhiko; Nagaoka, Masao
Journal of Chemical Research, Miniprint, 1985 , # 11 p. 3701 - 3715
反应条件
1,4-dithio-DL-threitol; human liver catechol-O-methyltransferase; magnesium chloride in water T=37°C; pH=7.4; 0.5 h; Enzyme kinetics; Further Variations:Reagents;
参考文献
Takemura, Hitomi; Uchiyama, Harue; Ohura, Takeshi; Sakakibara, Hiroyuki; Kuruto, Ryoko; Amagai, Takashi; Shimoi, Kayoko
Journal of Steroid Biochemistry and Molecular Biology, 2010 , vol. 118, # 1-2 p. 70 - 76
反应条件
in methanol; diethyl ether T=30°C; Rate constant;
参考文献
Teranishi; Fujii; Yamazaki; Miyabo
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3309 - 3314
