1,1-二甲基-4-氧代-哌啶鎓碘化物合成路线 （共 14 条）
参考文献
Chung, John Y. L.; Cvetovich, Raymond J.; McLaughlin, Mark; Amato, Joseph; Tsay, Fuh-Rong; Jensen, Mark; Weissman, Steve; Zewge, Daniel
Journal of Organic Chemistry, 2006 , vol. 71, # 22 p. 8602 - 8609
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6884868 B1, 2005 ;
US 6884868 B1
反应条件
in acetone T=25 - 30°C; 2 h; Title compound not separated from byproducts;
参考文献
Amato, Joseph S.; Chung, John Y. L.; Cvetovich, Raymond J.; Gong, Xiaoyi; McLaughlin, Mark; Reamer, Robert A.
Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1930 - 1933
反应条件
1: water; hydrochloric acid 2: diisopropyl ether View Scheme
参考文献
Howton
Journal of Organic Chemistry, 1945 , vol. 10, p. 277,278
反应条件
1: sodium; xylene 2: water; hydrochloric acid 3: diisopropyl ether View Scheme
参考文献
Howton
Journal of Organic Chemistry, 1945 , vol. 10, p. 277,278
反应条件
1: water; hydrochloric acid 2: isopropyl alcohol / in siedendem Isopropylalkohol View Scheme
参考文献
Cardwell; McQuillin
Journal of the Chemical Society, 1949 , p. 708,712
反应条件
1: 87 percent / sodium acrylate / H2O 2: 99 percent / Raney Ni; HCl / ethanol; propan-2-ol 3: thionyl chloride 4: magnesium / tetrahydrofuran / 5 h / 70 °C View Scheme
参考文献
Chung, John Y. L.; Cvetovich, Raymond J.; McLaughlin, Mark; Amato, Joseph; Tsay, Fuh-Rong; Jensen, Mark; Weissman, Steve; Zewge, Daniel
Journal of Organic Chemistry, 2006 , vol. 71, # 22 p. 8602 - 8609
反应条件
potassium carbonate in ethanol; water T=20 - 75°C; 13.5 h;
参考文献
ARES TRADING S.A.; JORAND-LEBRUN, Catherine; SWINNEN, Dominique; GERBER, Patrick; KULKARNI, Santosh
Patent: WO2012/130915 A1, 2012 ;
Location in patent: Page/Page column 55-56 ;
WO 2012/130915 A1
反应条件
sodium sulfide; sodium hydrogensulfide in diethyl ether; water 4 h; Heating;
参考文献
Garst, Michael E.; McBride, Bill J.; Johnson, Alan T.
Journal of Organic Chemistry, 1983 , vol. 48, # 1 p. 8 - 16
反应条件
acrylic acid sodium salt in water
参考文献
Chung, John Y. L.; Cvetovich, Raymond J.; McLaughlin, Mark; Amato, Joseph; Tsay, Fuh-Rong; Jensen, Mark; Weissman, Steve; Zewge, Daniel
Journal of Organic Chemistry, 2006 , vol. 71, # 22 p. 8602 - 8609
