5-(4-甲氧基苯基)-5-氧代戊腈合成路线 （共 6 条）
反应条件
sodium carbonate in water 12 - 15 h; Reflux;
参考文献
Streuff, Jan; Feurer, Markus; Bichovski, Plamen; Frey, Georg; Gellrich, Urs
Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8661 - 8664
反应条件
methanesulfonyl chloride T=0 - 20°C; 2 h; Yield given;
参考文献
Dillard, Robert D.; Hahn, Richard A.; McCullough, Doris; Carr, F. Patrick; Rinkema, Lynn E.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2768 - 2778
反应条件
1: 32 percent / CH2Cl2 / 3 h 2: methanesulfonyl chloride / 2 h / 0 - 20 °C View Scheme
参考文献
Dillard, Robert D.; Hahn, Richard A.; McCullough, Doris; Carr, F. Patrick; Rinkema, Lynn E.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2768 - 2778
反应条件
1: 32 percent / CH2Cl2 / 3 h 2: methanesulfonyl chloride / 2 h / 0 - 20 °C View Scheme
参考文献
Dillard, Robert D.; Hahn, Richard A.; McCullough, Doris; Carr, F. Patrick; Rinkema, Lynn E.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2768 - 2778
参考文献
Wisconsin Alumni Research Found.
Patent: US2842559 , 1954 ;
反应条件
(i) dihydropyrane, H2SO4, benzene, (ii) Na, (iii) /BRN= 471918/; Multistep reaction;
参考文献
Bogavac,M. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 4437 - 4442
