6-甲氧基异喹啉-1(2H)-酮合成路线 (共 3 条)
反应条件
trichlorophosphate 3 h; Heating / reflux;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/285773 A1, 2009 ;
Location in patent: Page/Page column 12 ;
US 20090285773 A1
反应条件
boron tribromide in dichloromethane T=0 - 20°C; 18 h;
参考文献
OTSUKA PHARMACEUTICAL CO., LTD.; OSHIMA, Kunio; MATSUMURA, Shuuji; YAMABE, Hokuto; ISONO, Naohiro; TAKEMURA, Noriaki; TAIRA, Shinichi; OSHIYAMA, Takashi; MENJO, Yasuhiro; NAGASE, Tsuyoshi; UEDA, Masataka; KOGA, Yasuo; NAKAYAMA, Sunao; TSUJIMAE, Kenji; ONOGAWA, Toshiyuki; TAI, Kuninori; ITOTANI, Motohiro
Patent: WO2011/21726 A2, 2011 ;
Location in patent: Page/Page column 419 ;
WO 2011/021726 A2
反应条件
N-bromosuccinmide in acetonitrile
参考文献
Bristol-Myers Squibb Company; Hiebert, Sheldon; Rajamani, Ramkumar; Sun, Li-Qiang; Mull, Eric; Gillis, Eric P.; Bowsher, Michael S.; Zhao, Qian; Meanwell, Nicholas A.; Renduchintala, Kishore V.; Sarkunam, Kandhasamy; Nagalakshmi, Pulicharla; Babu, P. V. K. Suresh; Scola, Paul Michael
Patent: US2013/115190 A1, 2013 ;
Location in patent: Page/Page column ;