1: With water; sodium hydroxide in ethanol
T=80°C;
2: With hydrogenchloride in water
pH=Ca. 7; Cooling with ice;
参考文献
Aurelio, Luigi; Valant, Celine; Figler, Heidi; Flynn, Bernard L.; Linden, Joel; Sexton, Patrick M.; Christopoulos, Arthur; Scammells, Peter J.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 20 p. 7353 - 7361
