1: K2CO3 / methanol / 3 h / 20 °C 2: 1.9 g / Et3N / CH2Cl2 / 12 h 3: 97 percent / Pd(PPh3)2Cl2; Et3N; formic acid / dimethylformamide / 1 h / 110 °C 4: trifluoroacetic acid / 1 h / 100 °C 5: 0.7 g / pyridine / 2 h / 0 °C 6: 75 percent / Pd(PPh3)2Cl2; Et3N; formic acid / dimethylformamide / 1 h / 110 °C 7: 68 percent / potassium permanganate / acetone / 3 h / 20 °C View Scheme

1: K2CO3 / methanol / 3 h / 20 °C 2: 1.9 g / Et3N / CH2Cl2 / 12 h 3: 97 percent / Pd(PPh3)2Cl2; Et3N; formic acid / dimethylformamide / 1 h / 110 °C 4: trifluoroacetic acid / 1 h / 100 °C 5: 0.7 g / pyridine / 2 h / 0 °C 6: 75 percent / Pd(PPh3)2Cl2; Et3N; formic acid / dimethylformamide / 1 h / 110 °C View Scheme