4-羟基-3-甲氧硼酸频哪醇酯合成路线 (共 4 条)
反应条件
1: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane T=80°C; 2: 2-methoxy-4-bromophenol; 4,4,5,5-tetramethyl-[1,3,2]dioxaborolane With triethylamine in 1,4-dioxane T=100°C; 20 h;
参考文献
US6680401 B1, ;
Page column 66 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C;
参考文献
HUTCHISON MEDIPHARMA LIMITED; Su, Wei-Guo; Deng, Wei; Ji, Jianguo
Patent: US2014/121200 A1, 2014 ;
Location in patent: Paragraph 0176; 0179; 0180 ;
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane; water
2.75 h; Heating / reflux;
参考文献
4 AZA Bioscience nv
Patent: WO2006/135993 A1, 2006 ;
Location in patent: Page/Page column 65-66 ;
反应条件
lithium hydroxide; palladium diacetate in tetrahydrofuran; water
T=20°C; Suzuki-Miyaura cross-coupling; 4 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Chemical Communications, 2006 , # 24 p. 2589 - 2591