(异丙烯基乙炔基)二甲基甲醇合成路线 （共 14 条）
反应条件
1: 2-methyl-1-butene-3-yne With n-butyllithium in tetrahydrofuran; hexane T=-78 - -20°C; 0.583333 h; Inert atmosphere; 2: acetone in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; 3: With water; ammonium chloride in tetrahydrofuran; hexane Inert atmosphere;
参考文献
Kern, Nicolas; Blanc, Aurelien; Miaskiewicz, Solene; Robinette, Michelle; Weibel, Jean-Marc; Pale, Patrick
Journal of Organic Chemistry, 2012 , vol. 77, # 9 p. 4323 - 4341
反应条件
methanol; sulfuric acid T=60 - 65°C;
参考文献
Dupont
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1911 , vol. 152, p. 198
Annales de Chimie (Cachan, France), 1913 , vol. <8>30, p. 512
反应条件
1: 1) BuLi / 1) THF, -78 deg C, 30 min, 2) THF, -78 to 20 deg C then 24 h, RT 2: MeOH, Amberlyst 15H / 1) THF, hexane View Scheme
参考文献
Hoffmann, H. M. R.; Krumwiede, D.; Mucha, B.; Oehlerking, H. H.; Prahst, G. W.
Tetrahedron, 1993 , vol. 49, # 40 p. 8999 - 9018
反应条件
methanol; Amberlyst 15H 1) THF, hexane; Yield given. Multistep reaction;
参考文献
Hoffmann, H. M. R.; Krumwiede, D.; Mucha, B.; Oehlerking, H. H.; Prahst, G. W.
Tetrahedron, 1993 , vol. 49, # 40 p. 8999 - 9018
参考文献
Vartanyan,S.A. et al.
Zhurnal Organicheskoi Khimii, 1965 , vol. 1, p. 2097 - 2101,2140 - 2143
反应条件
1: acidic aluminium oxide / 270 - 280 °C 2: ethyl magnesium bromide; diethyl ether View Scheme
参考文献
Alder; v. Brachel
Justus Liebigs Annalen der Chemie, 1957 , vol. 608, p. 195,198
反应条件
1: aq. HCl, AlCl3 2: aq. K2CO3 View Scheme
参考文献
Vartanyan,S.A. et al.
Zhurnal Organicheskoi Khimii, 1965 , vol. 1, p. 2097 - 2101,2140 - 2143
反应条件
potassium hydroxide; diethyl ether
参考文献
Nasarow
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1938 , p. 704
Chem. Zentralbl., 1939 , vol. 110, # II p. 3403
参考文献
Hoffmann, H. M. R.; Krumwiede, D.; Mucha, B.; Oehlerking, H. H.; Prahst, G. W.
Tetrahedron, 1993 , vol. 49, # 40 p. 8999 - 9018
参考文献
Nasarow; Jelisarowa
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1940 , p. 189
Chem.Abstr., 1942 , p. 742
