2-氨基-4,5-二甲氧基苯腈合成路线 （共 16 条）
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
National Science Council
Patent: US5158953 A1, 1992 ;
反应条件
toluene-4-sulfonic acid in methanol; water T=20°C; 1 h;
参考文献
Koutentis, Panayiotis A.; Michaelidou, Sophia S.
Tetrahedron, 2010 , vol. 66, # 32 p. 6032 - 6039
反应条件
indium(III) chloride T=170°C; P=760.051 Torr; 0.166667 h; Microwave irradiation;
参考文献
Loidreau, Yvonnick; Besson, Thierry
Tetrahedron, 2011 , vol. 67, # 26 p. 4852 - 4857
反应条件
T=200°C; 1 h; Microwave irradiationSealed vial;
参考文献
Loidreau, Yvonnick; Besson, Thierry
Tetrahedron, 2011 , vol. 67, # 26 p. 4852 - 4857
反应条件
in 2-ethoxy-ethanol 2 h; Reflux;
参考文献
Journal of Heterocyclic Chemistry, , vol. 48, # 6 p. 1407 - 1413
反应条件
1: 0.17 h / 90 °C / 760.05 Torr / Microwave irradiation 2: indium(III) chloride; formamide / 0.17 h / 150 °C / Microwave irradiation; Sealed vial View Scheme
参考文献
Loidreau, Yvonnick; Besson, Thierry
Tetrahedron, 2011 , vol. 67, # 26 p. 4852 - 4857
反应条件
2,6-dichloro-benzonitrile T=120°C; P=750.075 Torr; 4 h;
参考文献
Mizuno, Takumi; Mihara, Masatoshi; Nakai, Takeo; Iwai, Toshiyuki; Ito, Takatoshi
Synthesis, 2007 , # 16 p. 2524 - 2528
反应条件
1: 94 percent / CaCO3 / H2O; CH2Cl2 / 1) 0-5 deg C, 1 h; 2) 20 deg C, 20 h; 2: 90 percent / ethyl acetate / 20 h / 0 °C 3: 95 percent / ethyl acetate / 20 h / 60 °C 4: 86 percent / ammonium chloride / formamide / 20 h / 120 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 17, # 4 p. 797 - 798
反应条件
1: bis(trichloromethyl) carbonate With triethylamine; triphenyl-phosphine oxide in chlorobenzene T=20°C; 0.5 h; Cooling with ice; 2: 2-amino-4,5-dimethoxybenzonitrile in chlorobenzene T=120°C; 8 h;
参考文献
Li, Zhenhua; Wu, Danli; Zhong, Weihui
Heterocycles, 2012 , vol. 85, # 6 p. 1417 - 1426
反应条件
in N,N-dimethyl-formamide; mineral oil
参考文献
Pfizer Inc.
Patent: US3935213 A1, 1976 ;
