2-氨基-4-苯基-6-三氟甲基嘧啶合成路线 （共 5 条）
反应条件
sodium hydride in tetrahydrofuran T=40°C; 36 h;
参考文献
Guan, Hui-Ping; Tang, Xiao-Qing; Luo, Bing-Hao; Hu, Chang-Ming
Synthesis, 1997 , # 12 p. 1489 - 1494
反应条件
iron nitrate (III) in methanol T=40°C; 24 h;
参考文献
Bonacorso, Helio G.; Ferla, Adriana; Cechinel, Cleber A.; Zanatta, Nilo; Martins, Marcos A. P.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 2 p. 483 - 487
反应条件
in ethanol T=78°C; 8 h;
参考文献
Rawal, Ravindra K.; Tripathi, Rajkamal; Katti; Pannecouque, Christophe; De Clercq, Erik
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 9 p. 3134 - 3142
反应条件
1: Na2S2O4, NaHCO3 / acetonitrile; H2O / 6 h / 0 °C 2: 85 percent / NaH / tetrahydrofuran / 36 h / 40 °C View Scheme
参考文献
Guan, Hui-Ping; Tang, Xiao-Qing; Luo, Bing-Hao; Hu, Chang-Ming
Synthesis, 1997 , # 12 p. 1489 - 1494
反应条件
sodium isopropanolate 1.) isopropanol, 82 deg C, 1 h, 2.) 82 deg C, 11 h; Yield given. Multistep reaction;
参考文献
Kucerovy, Andrew; Mattner, Paul G.; Hathaway, Joel S.; Repic, Oljan
Synthetic Communications, 1990 , vol. 20, # 6 p. 913 - 917
