3-(三氟甲基)-5-对甲苯-1H-吡唑合成路线 （共 4 条）
反应条件
1: silver(l) oxide; sodium acetate / N,N-dimethyl-formamide / 20 °C / |Schlenk technique 2: N,N-dimethyl-formamide; toluene; water / 5 h / 45 °C / |Schlenk technique View Scheme
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
in water; N,N-dimethyl-formamide; toluene T=45°C; 5 h; Schlenk technique; regioselective reaction;
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
1: copper(l) iodide; potassium carbonate; N,N-dimethyl-cyclohexylamine / 36 h / 120 °C / |Schlenk technique; |Inert atmosphere 2: sulfuric acid / 4 h / 20 °C View Scheme
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
caesium carbonate; copper(I) oxide; trans-1,2-bis(2'-pyridylideneamino)cyclohexane
Conversion of starting material;
参考文献
Cellier, Pascal Philippe; Cristau, Henri-Jean; Spindler, Jean-Francis; Taillefer, Marc
Patent: US2003/236413 A1, 2003 ;
Location in patent: Page 26 ;
