(S)-3-氨基-4-(4-溴苯基)丁酸盐酸盐合成路线 （共 4 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 5 h;
参考文献
Helvetica Chimica Acta, , vol. 89, # 7 p. 1427 - 1441
反应条件
1: 93 percent / NaOH / methanol; H2O / 14 h / 20 °C 2: CF3COOH / CH2Cl2 / 5 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 89, # 7 p. 1427 - 1441
反应条件
1: 82 percent / AgCO2CF3 / H2O; triethylamine / 18 h / 0 - 20 °C 2: 93 percent / NaOH / methanol; H2O / 14 h / 20 °C 3: CF3COOH / CH2Cl2 / 5 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 89, # 7 p. 1427 - 1441
反应条件
1: N-methylmorpholine / tetrahydrofuran / 0.33 h / -20 °C 2: 674 mg / tetrahydrofuran / 16 h / 20 °C 3: 82 percent / AgCO2CF3 / H2O; triethylamine / 18 h / 0 - 20 °C 4: 93 percent / NaOH / methanol; H2O / 14 h / 20 °C 5: CF3COOH / CH2Cl2 / 5 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 89, # 7 p. 1427 - 1441
