3,5-二硝基苯甲酸甲酯合成路线 （共 42 条）
反应条件
1: in methanol T=85°C; 4 h; 2: With hydrogenchloride in methanol; water T=20°C; pH=~ 3;
参考文献
COMENTIS, INC.; PURDUE RESEARCH FOUNDATION
Patent: WO2009/42694 A1, 2009 ;
Location in patent: Page/Page column 99-100 ;
WO 2009/042694 A1
反应条件
sodium methylate; sodium in methanol; ethyl acetate
参考文献
Gellman, Samuel H.; Hayen, Ahlke; Schmitt, Margaret A.; Ngassa, Felix N.
Patent: US2004/116654 A1, 2004 ;
反应条件
1: methanol With lithium T=0°C; Inert atmosphere; 2: Methyl 3,5-dinitrobenzoate RefluxInert atmosphere;
参考文献
Brandt, Gary E. L.; Blagg, Brian S. J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 735 - 740
反应条件
lithium methanolate 4 h; Heating;
参考文献
Australian Journal of Chemistry, , vol. 34, # 6 p. 1319 - 1324
参考文献
Dwivedi, D.K.; Agarwala, B.V.; Dey, A.K.
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 4 p. 431 - 436
反应条件
formic acid; triethylamine; palladium on activated charcoal T=100°C; 1 h;
参考文献
Terpko, Marc O.; Heck, Richard F.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4992 - 4993
反应条件
methanol; ammonia Einleiten von Schwefelwasserstoff;
参考文献
Cohen; Mc Candlish
Journal of the Chemical Society, 1905 , vol. 87, p. 1265
反应条件
1: 63 percent / MeOLi / 4 h / Heating 2: 79 percent / 48percent aq. HBr, AcOH / 22 h / Heating View Scheme
参考文献
Herlt, Anthony J.; Kibby, Jeffrey J.; Rickards, Rodney W.
Australian Journal of Chemistry, 1981 , vol. 34, # 6 p. 1319 - 1324
反应条件
indium; iodine transesterification; 32 h; Heating;
参考文献
Ranu, Brindaban C.; Dutta, Pinak; Sarkar, Arunkanti
Journal of Organic Chemistry, 1998 , vol. 63, # 17 p. 6027 - 6028
反应条件
1: 63 percent / MeOLi / 4 h / Heating 2: 79 percent / 48percent aq. HBr, AcOH / 22 h / Heating 3: 100 percent / H2 / 10percent Pd/C / ethanol / 0.25 h / 760 Torr View Scheme
参考文献
Herlt, Anthony J.; Kibby, Jeffrey J.; Rickards, Rodney W.
Australian Journal of Chemistry, 1981 , vol. 34, # 6 p. 1319 - 1324
