2,5-二甲基-3-羟基苯甲酸合成路线 (共 2 条)
反应条件
1: With oleum, fuming sulfuric acid, 20 SO3; sulfuric acid T=110°C; 2 h; 2: With sodium hydroxide in water T=0°C; 3: With hydrogenchloride; potassium hydroxide more than 3 stages;
参考文献
PFIZER INC.
Patent: WO2005/26114 A1, 2005 ;
Location in patent: Page/Page column 88-89 ;
反应条件
potassium hydroxide Neat (no solvent);
参考文献
PFIZER INC.
Patent: WO2005/26114 A1, 2005 ;
Location in patent: Page/Page column 97 ;