2,5-二氯-3,6-二甲基吡嗪合成路线 （共 16 条）
反应条件
magnesium; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) 1.) THF; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Sato, Nobuhiro; Matsuura, Tomoyuki
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2345 - 2350
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane; hexane 4 h; Heating;
参考文献
Ohta, Akihiro; Inoue, Akira; Watanabe, Tokuhiro
Heterocycles, 1984 , vol. 22, # 10 p. 2317 - 2321
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1957 , vol. 79, p. 680,683
反应条件
sodium methylate T=120°C; 14 h;
参考文献
Sato, Nobuhiro; Kato, Yukihiro
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 6 p. 1677 - 1680
反应条件
phosphorus tribromide 24 h; Heating;
参考文献
Zhao, Liang; Perepichka, Igor F.; Tuerksoy, Figen; Batsanov, Andrei S.; Beeby, Andrew; Findlay, Karen S.; Bryce, Martin K.
New Journal of Chemistry, 2004 , vol. 28, # 8 p. 912 - 918
反应条件
pyridine; trichlorophosphate
T=160°C; 2 h; Autoclaveneat (no solvent);
参考文献
Wang, Han; Wen, Kun; Wang, Le; Xiang, Ye; Xu, Xiaocheng; Shen, Yongjia; Sun, Zhihua
Molecules, 2012 , vol. 17, # 4 p. 4533 - 4544
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
1: pyridine; acetic acid; bromine
2: POCl3
View Scheme
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
trichlorophosphate
Heating;
参考文献
Sato, Nobuhiro; Matsuura, Tomoyuki
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2345 - 2350
参考文献
Newbold; Spring
Journal of the Chemical Society, 1947 , p. 1183
