2,5-二氯-3,6-二甲基吡嗪合成路线 （共 16 条）
反应条件
trichlorophosphate
Heating; Yield given;
参考文献
Adachi, Jiro; Sato, Nobuhiro
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 871 - 875
反应条件
1: acetic acid; aqueous H2O2
2: SO2Cl2
View Scheme
参考文献
Newbold; Spring
Journal of the Chemical Society, 1947 , p. 1183
反应条件
1: acetic acid; aqueous H2O2
2: POCl3
View Scheme
参考文献
Baxter et al.
Journal of the Chemical Society, 1948 , p. 1859,1861
反应条件
1: 19 percent / K2S2O8, conc. H2SO4 / 48 h / Ambient temperature
2: 90 percent / sodium methoxide; conc. HCl / dioxane / 4 h / 110 °C
3: 38 percent / H2 / PtO2 / methanol / 40 °C / 2942.03 Torr
View Scheme
参考文献
Ohta, Akihiro; Yamamoto, Fusako; Arimura, Yasuhiko; Watanabe, Tokuhiro
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 781 - 784
反应条件
2-azidoethanol; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0)
T=120°C; P=29420.3 Torr; 16 h;
参考文献
Takeuchi; Suzuki; Sato
Synthesis, 1990 , vol. 1, # 10 p. 923 - 924
反应条件
1: 73 percent / CH3ONa / 14 h / 120 °C
2: tetrahydrothiophene 1,1-dioxide / 2 h / 40 - 45 °C
3: H2O / tetrahydrothiophene 1,1-dioxide / 70 deg C, 30 min; room temperature overnight
View Scheme
参考文献
Sato, Nobuhiro; Kato, Yukihiro
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 6 p. 1677 - 1680
