1: 4-hydroxy-benzonitrile With potassium tert-butylate in tetrahydrofuran; dimethyl sulfoxide 2.5 h; 2: 2-bromo-pyridine in tetrahydrofuran; dimethyl sulfoxide T=160°C; 115 h;

N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate in dichloromethane T=25°C; 15 h;