反应条件
1.1: 83 percent / HOAt; EDCI / CH2Cl2 / 6 h / 0 °C
2.1: Zn; 90percent aq. AcOH / 2 h / 0 °C
3.1: I2 / CH2Cl2; methanol / 2 h / 25 °C
4.1: 3 M HCl / dioxane / 0.5 h / 25 °C
5.1: HOAt; EDCI / CH2Cl2 / 6 h / 0 °C
6.1: TFA; anisole / 6 h / 25 °C
7.1: DMAP; EDCI / CH2Cl2 / 0.5 h / 25 °C
7.2: CH2Cl2 / 72 h / 25 °C
View Scheme
参考文献
Boger; Ichikawa; Tse; Hedrick; Jin
Journal of the American Chemical Society, 2001 , vol. 123, # 4 p. 561 - 568
