Z-LEU-GLY-OH合成路线 （共 16 条）
反应条件
tetrahydrofuran; water; anhydrous magnesium carbonate
参考文献
Farrington et al.
Journal of the Chemical Society, 1957 , p. 1407,1410
参考文献
Handford; Jones; Young; Johnson
Journal of the Chemical Society. Perkin transactions 1, 1965 , p. 6814 - 6827
参考文献
Weygand,F.; Steglich,W.
Chemische Berichte, 1960 , vol. 93, p. 2983 - 3005
反应条件
(i) ClCO2Et, Et3N, acetone, (ii) /BRN= 635782/, aq. NaOH; Multistep reaction;
参考文献
Beecham,A.F.
Australian Journal of Chemistry, 1963 , vol. 16, p. 160 - 164
反应条件
1: 60 percent / EtN(i-Pr)2 / anodic oxidation; Pt electrodes, i = 250 mA*cm-2, current equiv.: 7.0 F/mol
2: 84 percent / 0.5 N HCl / 4 h
View Scheme
参考文献
Seebach, Dieter; Charczuk, Roland; Gerber, Christian; Renaud, Philippe; Berner, Heinz; Schneider, Helmut
Helvetica Chimica Acta, 1989 , vol. 72, p. 401 - 425
反应条件
1: 1 M ethylchloroformate, 0.04 M N-methylmorpholine, 0.01 M HCl / tetrahydrofuran / 0.05 h / Ambient temperature
2: 0.02 M HCl / 0.17 h
3: 48 percent / 1 N aq. HCl / diethyl ether
View Scheme
参考文献
Yagisawa, Shiroki; Urakami, Masako
Tetrahedron Letters, 1996 , vol. 37, # 42 p. 7557 - 7560
