3-溴-2,4-二甲基吡啶合成路线 (共 5 条)
反应条件
sulfuric acid; bromine T=155 - 175°C; 24 h;
参考文献
Dunn, Allan D.; Guillermic, Sandrine
Zeitschrift fuer Chemie (Stuttgart, Germany), 1988 , vol. 28, # 2 p. 59 - 60
参考文献
Hoechst Aktiengesellschaft
Patent: US5004748 A1, 1991 ;
参考文献
Smith Kline and French Laboratories Limited
Patent: US4154834 A1, 1979 ;
US 4154834 A
反应条件
1: With isopropylmagnesium chloride in tetrahydrofuran T=20°C; 2: With methanol regioselective reaction;
参考文献
Thalhammer, Armin; Mecinovic, Jasmin; Loenarz, Christoph; Tumber, Anthony; Rose, Nathan R.; Heightman, Tom D.; Schofield, Christopher J.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 1 p. 127 - 135
参考文献
Hoechst Aktiengesellschaft
Patent: US5004748 A1, 1991 ;