3-(4-甲氧基苯基）吡唑合成路线 （共 15 条）
反应条件
hydrazine solvate in acetid acid T=85°C; 16 h;
参考文献
Gogsig, Thomas M.; Nielsen, Dennis U.; Lindhardt, Anders T.; Skrydstrup, Troels
Organic Letters, 2012 , vol. 14, # 10 p. 2536 - 2539
反应条件
1: 24 h; Heating / reflux; 2: With acetic acid; hydrazine in ethanol; water T=0 - 20°C; 3: With sodium hydrogencarbonate in water
参考文献
Eisai Co., Ltd.
Patent: EP1382603 A1, 2004 ;
Location in patent: Page 43 ;
反应条件
1: 4-methoxy-benzaldehyde With toluene-4-sulfonic acid hydrazide in acetonitrile T=20°C; 3 h; 2: With sodium hydroxide in acetonitrile T=20°C; 0.333333 h; 3: 1-vinyl-imidazole in acetonitrile T=50°C; 48 h;
参考文献
Aggarwal, Varinder K.; De Vicente, Javier; Bonnert, Roger V.
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5381 - 5383
反应条件
hydrazine monohydrochloride; water in 1,4-dioxane T=80°C; 0.25 h;
参考文献
Levi, Lucilla; Boersch, Christina; Gers, Charlotte F.; Merkul, Eugen; Mueller, Thomas J. J.
Molecules, 2011 , vol. 16, # 11 p. 9340 - 9356
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 1,4-dioxane / 2 h / 20 °C / Inert atmosphere 2: hydrazine monohydrochloride; water / 1,4-dioxane / 0.25 h / 80 °C View Scheme
参考文献
Gogsig, Thomas M.; Nielsen, Dennis U.; Lindhardt, Anders T.; Skrydstrup, Troels
Organic Letters, 2012 , vol. 14, # 10 p. 2536 - 2539
反应条件
hydrazine hydrate in chloroform T=20°C;
参考文献
Allahyari-Devin, Maryam; Abedi, Behnam; Navidpour, Latifeh; Shafiee, Abbas
Journal of the Iranian Chemical Society, 2013 , vol. 10, # 1 p. 43 - 53
反应条件
hydraziniumdihydrochloride in ethanol 2 h; Heating; Yield given;
参考文献
Takahashi, Kazumasa; Urano, Yuko; Ogura, Katsuyuki; Iida, Hirotada
Synthesis, 1985 , # 6/7 p. 690 - 691
反应条件
1: 1.) lithium diisopropylamide / HMPT, THF, 1.) -78 deg C, 30 min, 2.) -78 deg C, 30 min, room temp., 5h 2: hydrazine dihydrochloride / ethanol / 2 h / Heating View Scheme
参考文献
Takahashi, Kazumasa; Urano, Yuko; Ogura, Katsuyuki; Iida, Hirotada
Synthesis, 1985 , # 6/7 p. 690 - 691
反应条件
hydrazine in water T=25°C; Kinetics;
参考文献
Um, Ik-Hwan; Lee, Eun-Ju; Seok, Jin-Ah; Kim, Kyung-Hee
Journal of Organic Chemistry, 2005 , vol. 70, # 19 p. 7530 - 7536
反应条件
1: sodium ethanolate / diethyl ether / 0 - 20 °C 2: hydrazine hydrate; acetic acid / ethanol / |Reflux View Scheme
参考文献
Allahyari-Devin, Maryam; Abedi, Behnam; Navidpour, Latifeh; Shafiee, Abbas
Journal of the Iranian Chemical Society, 2013 , vol. 10, # 1 p. 43 - 53
