4-(三氟乙酰氨基)苯酚合成路线 （共 12 条）
反应条件
in dichloromethane 0.5 h; Heating;
参考文献
Barnard; Storr; O'Neill; Park
Journal of Pharmacy and Pharmacology, 1993 , vol. 45, # 8 p. 736 - 744
反应条件
3 platinum on carbon; water; hydrogen in N,N-dimethyl-formamide T=79.84°C; P=907.591 Torr; 20 h;
参考文献
Quartarone, Giuseppe; Ronchin, Lucio; Tosetto, Alice; Vavasori, Andrea
Applied Catalysis A: General, 2014 , vol. 475, p. 169 - 178
反应条件
5 rhodium-on-charcoal; water; hydrogen; trifluoroacetic acid in acetonitrile T=79.84°C; P=907.591 Torr; 3 h;
参考文献
Quartarone, Giuseppe; Ronchin, Lucio; Tosetto, Alice; Vavasori, Andrea
Applied Catalysis A: General, 2014 , vol. 475, p. 169 - 178
反应条件
triethylamine; trichloroacetonitrile; triphenylphosphine in acetonitrile T=20°C; 2 h; Inert atmosphere;
参考文献
Kim, Joong-Gon; Jang, Doo Ok
Tetrahedron Letters, 2010 , vol. 51, # 4 p. 683 - 685
反应条件
pyridine; sodium chloride; trifluoroacetic anhydride in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; tert-butyl methyl ether; dimethyl sulfoxide; acetonitrile
参考文献
Sterling Drug Inc.
Patent: US4835180 A1, 1989 ;
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran 19 h; Heating;
参考文献
Prashad; Hu; Har; Repic; Blacklock
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9957 - 9961
反应条件
in diethyl ether T=20°C; 1 h;
参考文献
Keumi, Takashi; Shimada, Masakazu; Morita, Toshio; Kitajima, Hidehiko
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 8 p. 2252 - 2256
反应条件
1: H2 / Pd-C / ethanol / 3 h / Ambient temperature 2: trifluoroacetic acid / 1 h View Scheme
参考文献
Borbas; Liptak
Carbohydrate Research, 1993 , vol. 241, p. 99 - 116
反应条件
in anhydrous xylene 6.5 h; Reflux;
参考文献
Ohtaka, Junpei; Sakamoto, Takeshi; Kikugawa, Yasuo
Tetrahedron Letters, 2009 , vol. 50, # 15 p. 1681 - 1683
反应条件
trifluoroacetic acid 1.) 60 deg C, 4 h, 2.) 0 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Haga, Naoki; Endo, Yasuyuki; Kataoka, Ken-Ichiro; Yamaguchi, Kentaro; Shudo, Koichi
Journal of the American Chemical Society, 1992 , vol. 114, # 25 p. 9795 - 9806
