1H-吡唑并[3,4-c]吡啶合成路线 （共 7 条）
反应条件
potassium carbonate; ethanethiol in N,N-dimethyl-formamide
参考文献
Zeneca Limited
Patent: US5300478 A1, 1994 ;
参考文献
Zeneca Limited
Patent: US5300478 A1, 1994 ;
参考文献
Zeneca Limited
Patent: US5300478 A1, 1994 ;
反应条件
iodine; potassium hydroxide in N,N-dimethyl-formamide T=20°C; 16 h;
参考文献
NOVARTIS AG; ALTMANN, Eva; HOMMEL, Ulrich; LORTHIOIS, Edwige Liliane Jeanne; MAIBAUM, Juergen Klaus; OSTERMANN, Nils; QUANCARD, Jean; RANDL, Stefan Andreas; VULPETTI, Anna
Patent: WO2014/2051 A2, 2014 ;
Location in patent: Page/Page column 54 ;
反应条件
1: concd. sulfuric acid; nitric acid / 95 °C 2: aq. hydrochloric acid; stannous chloride / Heating View Scheme
参考文献
Heterocycles, , vol. 51, # 7 p. 1661 - 1667
反应条件
sodium hypobromide in water T=0°C; 1 h;
参考文献
Milhavet; Bernal; Gueiffier; Contastin; Chapat; Teulade; Carpy; Grassy
Archiv der Pharmazie, 1989 , vol. 322, # 12 p. 885 - 887
反应条件
chlorine in water
1 h;
参考文献
Milhavet; Bernal; Gueiffier; Contastin; Chapat; Teulade; Carpy; Grassy
Archiv der Pharmazie, 1989 , vol. 322, # 12 p. 885 - 887
