7-氟-2-羟基-4-甲基喹啉合成路线 （共 2 条）
反应条件
1: With sulfuric acid T=0 - 95°C; 0.25 h; 2: With ammonia in water
参考文献
ASTRAZENECA AB
Patent: WO2005/66132 A1, 2005 ;
Location in patent: Page/Page column 41 ;
WO 2005/066132 A1
反应条件
1: in tetrahydrofuran Condensation; 12 h; Heating; 2: With sulfuric acid T=80°C; Cyclization; 0.5 h;
参考文献
Kato, Taka-Aki; Hakura, Atsushi; Mizutani, Takaharu; Saeki, Ken-Ichi
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2000 , vol. 465, # 1-2 p. 173 - 182
