4-乙烯基-苯甲酸乙基酯合成路线 （共 24 条）
反应条件
anhydrous potassium trimethylsilanolate; triphenyl-phosphine oxide; bis(dibenzylideneacetone)-palladium(0) in N,N-dimethyl-formamide T=25 - 49°C; 0.5 h;
参考文献
Denmark, Scott E.; Butler, Christopher R.
Journal of the American Chemical Society, 2008 , vol. 130, # 11 p. 3690 - 3704
反应条件
1: 4-amino-benzoic acid ethyl ester With tetrafluoroboric acid; sodium nitrite in water T=0 - 5°C; Diazotization; 0.5 h; 2: potassium vinyl trifluoroborate With bis(tri-o-tolylphosphine)palladium acetate in methanol T=20°C; Arylation; 2 h;
参考文献
Darses, Sylvain; Michaud, Guillaume; Genet, Jean-Pierre
European Journal of Organic Chemistry, 1999 , # 8 p. 1875 - 1883
反应条件
palladium diacetate; 4-H2F8-TPP in methanol; water T=20°C;
参考文献
Darses, Sylvain; Pucheault, Mathieu; Genet, Jean-Pierre
European Journal of Organic Chemistry, 2001 , # 6 p. 1121 - 1128
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=20°C; Alkylation; 1 h;
参考文献
Denmark, Scott E.; Wang, Zhigang
Synthesis, 2000 , # 7 p. 999 - 1003
反应条件
1: D4v With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 0.166667 h; 2: 4-iodobenzoic acid ethyl ester With bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=20°C; 0.166667 h;
参考文献
Denmark, Scott E.; Wang, Zhigang
Journal of Organometallic Chemistry, 2001 , vol. 624, # 1-2 p. 372 - 375
反应条件
potassium carbonate; trifuran-2-yl-phosphane; palladium dichloride in dimethyl sulfoxide T=35°C; 19 h;
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Chen, Jinshui; Yada, Akira; Hiyama, Tamejiro
Journal of Organometallic Chemistry, 2007 , vol. 692, # 1-3 p. 585 - 603
反应条件
potassium phosphate; [RhCl(η2:η2-cycloocta-1,5-diene)]2; 1,1-dimethylpropan-1-ol; 1,4-di(diphenylphosphino)-butane in toluene T=100°C; 24 h; Inert atmosphere;
参考文献
Yu, Jung-Yi; Kuwano, Ryoichi
Angewandte Chemie, International Edition, 2009 , vol. 48, # 39 p. 7217 - 7220
Angewandte Chemie, 2009 , vol. 121, # 39 p. 7353 - 7356
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; 12 h;
参考文献
Cho, So-Hye; Ma, Baoqing; Nguyen, SonBinh T.; Hupp, Joseph T.; Albrecht-Schmitt, Thomas E.
Chemical Communications, 2006 , # 24 p. 2563 - 2565
反应条件
tetrabutyl ammonium fluoride; palladium (II) bromide; biphenyl-2-yl-di-tert-butyl-phosphane in tetrahydrofuran T=50°C; 5 h;
参考文献
Denmark, Scott E.; Butler, Christopher R.
Organic Letters, 2006 , vol. 8, # 1 p. 63 - 66
反应条件
complex of lt;PdCl(π-C3H5)gt;2 and N-(2-diphenylphosphinobenzylidene)-2-phenylethylamine in toluene T=90°C; 43 h;
参考文献
Shirakawa, Eiji; Yoshida, Hiroto; Takaya, Hidemasa
Tetrahedron Letters, 1997 , vol. 38, # 21 p. 3759 - 3762
