1-(苄氨基)-2-丙醇合成路线 （共 12 条）
反应条件
calcium trifluoromethane sulfonate in acetonitrile T=20°C; 4 h;
参考文献
Cepanec, Ivica; Litvic, Mladen; Mikuldas, Hrvoje; Bartolincic, Anamarija; Vinkovic, Vladimir
Tetrahedron, 2003 , vol. 59, # 14 p. 2435 - 2439
反应条件
sodium tetrahydroborate in methanol T=25°C; 3 h;
参考文献
SCHERING CORPORATION
Patent: WO2006/60461 A1, 2006 ;
Location in patent: Page/Page column 148-149 ;
WO 2006/060461 A1
反应条件
ethanol anschliessende Hydrierung an Raney-Nickel;
参考文献
Freifelder et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 4320,4323
反应条件
in diethyl ether 2 h; Ambient temperature;
参考文献
Yamada, Jun-ichi; Yumoto, Masatoshi; Yamamoto, Yoshinori
Tetrahedron Letters, 1989 , vol. 30, # 32 p. 4255 - 4258
反应条件
in acetonitrile Alkylation; 0.5 h;
参考文献
Dinsmore; Zartman
Tetrahedron Letters, 2000 , vol. 41, # 33 p. 6309 - 6312
反应条件
NaOD; sodium salt of phosphorous acid in acetonitrile-D3; water-d2 T=25°C; 5 h; Product distribution;
参考文献
Schmidt; Schmidt, Brigitte F.; Snyder; Snyder, Emily J.; Carroll; Carroll, Robin M.; Farnsworth; Farnsworth, David W.; Michejda; Michejda, Christopher J.; Smith R.H.; Smith Jr., Richard H.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8660 - 8665
参考文献
Boivin
Canadian Journal of Chemistry, 1958 , vol. 36, p. 1405,1406
Full Text Show Details
Wilson
Journal of the Chemical Society, 1952 , p. 3524,3526
反应条件
sodium hydride 1.) THF, reflux, 0.5 h, 2.) THF, reflux, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hu; Cassady
Synthetic Communications, 1995 , vol. 25, # 6 p. 907 - 913
反应条件
1: sat. NaHCO3 / ethyl acetate / 0.33 h / 0 °C 2: 98 percent / DMSO; (COCl)2; Et3N / CH2Cl2 / 0.75 h / -78 - 20 °C 3: 4 Angstroem molecular sieves; sodium triacetoxyborohydride / 1,2-dichloro-ethane / 48 h / 0 - 20 °C 4: 91 percent / hydrogen / Pd(OH)2/C / methanol / 4 h View Scheme
参考文献
Dinsmore; Zartman
Tetrahedron Letters, 2000 , vol. 41, # 33 p. 6309 - 6312
反应条件
ethanol; water
anschliessendes Hydrieren an Platin;
参考文献
Freifelder et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 4320,4323
Full Text Show Details
Abbott Labor.
Patent: US2828328 , 1955 ;
