双环[2.2.2]辛烷-3-酮合成路线 （共 8 条）
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide 1) THF/hexane 30 min, -78 deg C 2a) -78 deg C, 20 min 2b) 15 min, r.t.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Santiago, Ana N.; Takeuchi, Ken'ichi; Ohga, Yasushi; Nishida, Mitsuo; Rossi, Roberto A.
Journal of Organic Chemistry, 1991 , vol. 56, # 4 p. 1581 - 1584
参考文献
Ye, Qing; Jones Jr., Maitland; Chen, Ting; Shevlin, Philip B.
Tetrahedron Letters, 2001 , vol. 42, # 40 p. 6979 - 6981
反应条件
in tetrahydrofuran; water Irradiation;
参考文献
Critch,S.C.; Fallis,A.G.
Canadian Journal of Chemistry, 1977 , vol. 55, p. 2845 - 2851
反应条件
sodium hydrogencarbonate Irradiation;
参考文献
Critch,S.C.; Fallis,A.G.
Canadian Journal of Chemistry, 1977 , vol. 55, p. 2845 - 2851
反应条件
sodium hydrogencarbonate in methanol
Irradiation;
参考文献
Critch,S.C.; Fallis,A.G.
Canadian Journal of Chemistry, 1977 , vol. 55, p. 2845 - 2851
反应条件
in benzene
Irradiation;
参考文献
Critch,S.C.; Fallis,A.G.
Canadian Journal of Chemistry, 1977 , vol. 55, p. 2845 - 2851
反应条件
potassium hydride
1.) DMF, 2.) DMF; Multistep reaction;
参考文献
Kirby, Anthony J.; Williams, Nicholas H.
Journal of the Chemical Society, Chemical Communications, 1991 , # 22 p. 1644 - 1645
反应条件
1: 78 percent / NH2OH*HCl, CH3COONa / methanol; H2O / 4 h / Heating
2: 79 percent / NaBH3CN, HCl / methanol / 4 h
View Scheme
参考文献
Maskill, H.; Thompson, John T.; Wilson, Alan A.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 10 p. 1693 - 1704
