1.1: LDA / tetrahydrofuran / 1 h / -78 °C 1.2: 60 percent / tetrahydrofuran / 0.25 h / -78 °C 2.1: aq. (NH4)2Ce(NO3)6 / acetonitrile / 16 h / 0 °C View Scheme

1: With potassium hydroxide; N-benzyl quinidinium chloride in toluene T=-45°C; 40 h; 2: With ammonium formate; palladium on activated charcoal in methanol T=0 - 20°C; Title compound not separated from byproducts;