3-氨基-5-苯基-1,2,4-噻二唑合成路线 （共 21 条）
反应条件
in acetone 1 h; Heating; Yields of byproduct given;
参考文献
Kurzer, Frederick
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 311 - 314
反应条件
(i) NaNO2, aq. HBr, Cu, (ii) (heating); Multistep reaction;
参考文献
Ginsberg,A.; Goerdeler,J.
Chemische Berichte, 1961 , vol. 94, p. 2043 - 2060
反应条件
(i) NaNO2, aq. HCl, Cu, (ii) (heating); Multistep reaction;
参考文献
Ginsberg,A.; Goerdeler,J.
Chemische Berichte, 1961 , vol. 94, p. 2043 - 2060
反应条件
1: 70 percent / NaNO2, HCl 2: 16 percent / aq. NaOH / 48 h / Ambient temperature 3: 50 percent / NaOH, water / ethanol / 1.) 100 deg C, 2 min, 2.) room temperature, 30 min View Scheme
参考文献
Newton, Christopher G.; Ollis, W. David; Wright, Derek E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 75 - 84
反应条件
1: 70 percent / NaNO2, HCl
2: 16 percent / aq. NaOH / 48 h / Ambient temperature
View Scheme
参考文献
Newton, Christopher G.; Ollis, W. David; Wright, Derek E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 75 - 84
反应条件
1: 70 percent / NaNO2, HCl
2: 8 percent / aq. NaOH / 48 h / Ambient temperature
View Scheme
参考文献
Kurzer,F.; Taylor,S.A.
Journal of the Chemical Society, 1960 , p. 3234 - 3239
反应条件
pyridine
T=100°C; 4 h;
参考文献
Newton, Christopher G.; Ollis, W. David; Wright, Derek E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 75 - 84
反应条件
1: 82 percent / acetone / 1 h / Heating
2: 85 percent / 3M aq. NaOH / 0.1 h / Heating
3: 68 percent / 1.5M aq. NaOH, 6percent H2O2 / 0.13 h / 75 - 80 °C
View Scheme
参考文献
Kurzer, Frederick
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 311 - 314
反应条件
1: 82 percent / acetone / 1 h / Heating
2: 85 percent / 3M aq. NaOH / 0.1 h / Heating
View Scheme
参考文献
Kurzer, Frederick; Secker, Jane L.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 355 - 360
反应条件
2: (i) Py, (ii) aq. HCl
View Scheme
参考文献
Shoeb,A. et al.
Journal of the Indian Chemical Society, 1963 , vol. 40, p. 369 - 372
