(1H-苯并咪唑-2-基)-苄胺合成路线 （共 11 条）
反应条件
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C;
参考文献
Wan, Zhao-Kui; Ousman, Erena Farah; Papaioannou, Nikolaos; Saiah, Eddine
Tetrahedron Letters, 2011 , vol. 52, # 32 p. 4149 - 4152
反应条件
polymer supported carbodiimide in tetrahydrofuran T=70°C; 22 h;
参考文献
Cee, Victor J.; Downing, Nicholas S.
Tetrahedron Letters, 2006 , vol. 47, # 22 p. 3747 - 3750
反应条件
sodium tetrahydroborate; N-ethyl-N,N-diisopropylamine in methanol; toluene
参考文献
Tularik, Inc
Patent: US2003/144286 A1, 2003 ;
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; potassium carbonate; butan-1-ol T=130°C; 12 h;
参考文献
Li, Feng; Kang, Qikai; Shan, Haixia; Chen, Lin; Xie, Jianjiang
European Journal of Organic Chemistry, 2012 , # 26 p. 5085 - 5092
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; potassium carbonate T=130°C; 12 h; regioselective reaction;
参考文献
Li, Feng; Kang, Qikai; Shan, Haixia; Chen, Lin; Xie, Jianjiang
European Journal of Organic Chemistry, 2012 , # 26 p. 5085 - 5092
参考文献
Blythin; Kaminski; Domalski; Spitler; Solomon; Conn; Wong; Verbiar; Bober; Chiu
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1099 - 1113
反应条件
1.1: imidazole / acetonitrile / 3.17 h / 0 - 20 °C 1.2: 64 percent / acetonitrile / 20 - 50 °C 2.1: yellow HgO; sulfur / ethanol / 2 h / Heating View Scheme
参考文献
Scheffer, Ute; Strick, Andreas; Ludwig, Verena; Peter, Sascha; Kalden, Elisabeth; Goebel, Michael W.
Journal of the American Chemical Society, 2005 , vol. 127, # 7 p. 2211 - 2217
反应条件
1.1: imidazole / acetonitrile / 3.17 h / 0 - 20 °C 1.2: 64 percent / acetonitrile / 20 - 50 °C 2.1: yellow HgO; sulfur / ethanol / 2 h / Heating View Scheme
参考文献
Scheffer, Ute; Strick, Andreas; Ludwig, Verena; Peter, Sascha; Kalden, Elisabeth; Goebel, Michael W.
Journal of the American Chemical Society, 2005 , vol. 127, # 7 p. 2211 - 2217
参考文献
Lan, Ping; Romero, F. Anthony; Malcolm, Threshia S.; Stevens, Benjamin D.; Wodka, Dariusz; Makara, Gergely M.
Tetrahedron Letters, 2008 , vol. 49, # 12 p. 1910 - 1914
反应条件
1: 47 percent / POCl3 / 4.5 h / Heating 2: 88 percent / 5 h / 195 - 200 °C View Scheme
参考文献
Blythin; Kaminski; Domalski; Spitler; Solomon; Conn; Wong; Verbiar; Bober; Chiu
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1099 - 1113
