3,4,5-三甲基-1H-吡咯-2-羧醛合成路线 （共 8 条）
反应条件
trichlorophosphate T=20°C; 2 h;
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
1: 65 percent / KOH / ethane-1,2-diol / 5 h / Heating 2: 73 percent / POCl3 / 2 h / 20 °C View Scheme
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
1: 70 percent / Zn, AcOH / 1 h / Heating 2: 65 percent / KOH / ethane-1,2-diol / 5 h / Heating 3: 73 percent / POCl3 / 2 h / 20 °C View Scheme
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
sodium hydroxide; benzoyl chloride 1.) ethylene glycol, reflux 45 min, 2.) toluene, -5-0 deg C, 1 h; Yield givenMultistep reaction;
参考文献
Lash, Timothy D.; Mani, Ukti N.; Drinan, Martin A.; Zhen, Chun; Hall, Troii; Jones, Marjorie A.
Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 464 - 477
反应条件
in trifluoroacetic acid Yield given;
参考文献
Swanson, Kristin L.; Snow, Kevin M.; Jeyakumar; Smith, Kevin M.
Tetrahedron, 1991 , vol. 47, # 4-5 p. 685 - 696
反应条件
1: trifluoroacetic acid / 0.17 h / 20 °C View Scheme
参考文献
Battersby, Alan R.; Fookes, Christopher J. R.; Snow, Roger J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2733 - 2741
参考文献
Battersby, Alan R.; Fookes, Christopher J. R.; Snow, Roger J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2733 - 2741
反应条件
sodium hydroxide; hydrazine hydrate; 1,2-bis-(2-hydroxyethoxy)-ethane
参考文献
Treibs; Derra-Scherer
Justus Liebigs Annalen der Chemie, 1954 , vol. 589, p. 188,194
