2-巯基-5-甲基苯并咪唑合成路线 （共 29 条）
反应条件
3,3-dimethyldioxirane; magnesium sulfate in dichloromethane; acetone T=25°C;
参考文献
Frachey, Giuseppe; Crestini, Claudia; Bernini, Roberta; Saladino, Raffaele; Mincione, Enrico
Heterocycles, 1994 , vol. 38, # 12 p. 2621 - 2630
反应条件
ammonia; 3,3-dimethyldioxirane in dichloromethane; acetone T=25°C;
参考文献
Frachey, Giuseppe; Crestini, Claudia; Bernini, Roberta; Saladino, Raffaele; Mincione, Enrico
Heterocycles, 1994 , vol. 38, # 12 p. 2621 - 2630
反应条件
ammonia; ozone in dichloromethane T=25°C;
参考文献
Saladino, Raffaele; Crestini, Claudia; Occhionero, Francesca; Nicoletti, Rosario
Synthetic Communications, 1996 , vol. 26, # 17 p. 3241 - 3251
反应条件
sodium hydroxide in dichloromethane; water
参考文献
Wockhardt Europe Limited
Patent: US6245913 B1, 2001 ;
反应条件
potassium hydroxide in ethanol
6 h; Reflux;
参考文献
Dubey; Naidu; Reddy, P.V.V. Prasada; Mahesh Kumar; Vineel, B. George
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 9 p. 1443 - 1446
参考文献
Rebstock et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 5831
反应条件
potassium hydroxide in ethanol; water
T=5 - 10°C; 2.5 h;
参考文献
Kuraray Co., Ltd.
Patent: US6350876 B2, 2002 ;
Location in patent: Referential example 1 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=110°C; 2 h;
参考文献
Aventis Pharma S.A.
Patent: EP1746097 A1, 2007 ;
Location in patent: Page/Page column 41 ;
EP 1746097 A1
反应条件
N-ethyl-N,N-diisopropylamine in acetone
T=20°C; 0.0833333 h; Sonication;
参考文献
Deligeorgiev, Todor; Kaloyanova, Stefka; Lesev, Nedyalko; Vaquero, Juan J.
Ultrasonics Sonochemistry, 2010 , vol. 17, # 5 p. 783 - 788
