(R)-(+)-1-(4-氯苯基)乙胺合成路线 （共 14 条）
反应条件
1: With C9H16BNO in tetrahydrofuran T=20°C; 24 h; 2: With borane-THF in tetrahydrofuran 24 h; Reflux; optical yield given as percent eeenantioselective reactionFurther stages;
参考文献
Pakulski, Marcin M.; Mahato, Sanjit K.; Bosiak, Mariusz J.; Krzeminski, Marek P.; Zaidlewicz, Marek
Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 716 - 721
反应条件
1: With [((R)-tol-binap)RuCl2(DMF)x]; ammonia; ammonium formate in methanol T=85°C; Leuckart-Wallach reaction; 24 h; 2: With hydrogenchloride in ethanol 1 h; Heating; Title compound not separated from byproducts;
参考文献
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962,3
Title/Abstract Full Text Show Details
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962
反应条件
6-(1,2:3,4-di-O-isopropylidene-α-D-galactopyranosyl) hydrogen phthalate in isopropyl alcohol Heating;
参考文献
Mereyala, Hari Babu; Fatima, Liyakat; Pola, Pallavi
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 585 - 587
反应条件
Ni T=110°C; 2 h; Inert atmosphere;
参考文献
Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E.
European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628
反应条件
borane-THF; C19H23BNO3(1-)*H(1+) in tetrahydrofuran; 1,4-dioxane T=0°C; Inert atmosphere; enantioselective reaction;
参考文献
Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327
反应条件
glucose dehydrogenase; (R)-alanine; transaminase ATA-117; nicotinamide adenine dinucleotide; sodium hydroxide; lactate dehydrogenase T=50°C; pH=8; 5 h; aq. phosphate bufferEnzymatic reaction; enantioselective reaction;
参考文献
Pakulski, Marcin M.; Mahato, Sanjit K.; Bosiak, Mariusz J.; Krzeminski, Marek P.; Zaidlewicz, Marek
Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 716 - 721
反应条件
ammonium cerium(IV) nitrate in methanol; water T=25°C; 12 h;
参考文献
Cheemala, Murthy N.; Knochel, Paul
Organic Letters, 2007 , vol. 9, # 16 p. 3089 - 3092
反应条件
1: hydrogen / (RFc)-1-Ph2P-2-((S)-MeO(2-Py)CH)ferrocene iridium complex / toluene; methanol / 4 h / 25 °C / 7500.75 Torr 2: Ce(NH4)2(NO3)6 / methanol; H2O / 12 h / 25 °C View Scheme
参考文献
Cheemala, Murthy N.; Knochel, Paul
Organic Letters, 2007 , vol. 9, # 16 p. 3089 - 3092
反应条件
1: With (Ph)2SiH2; silver trifluoromethanesulfonate in tetrahydrofuran T=20°C; 25 h; 2: With hydrogenchloride in tetrahydrofuran; methanol Further stages. Title compound not separated from byproducts.;
参考文献
Takei; Nishibayashi; Ishii; Mizobe; Uemura; Hidai
Chemical Communications, 2001 , # 22 p. 2360 - 2361
反应条件
L-amino acid oxidase; ATA-113; pyridoxal 5'-phosphate; 2-oxo-propionic acid T=30°C; pH=8; 3 h; Resolution of racemateaq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
O'Reilly, Elaine; Iglesias, Cesar; Turner, Nicholas J.
ChemCatChem, 2014 , vol. 6, # 4 p. 992 - 995
