1H-2-甲基-3-氨乙基吲哚合成路线 (共 17 条)
参考文献
Justus Liebigs Annalen der Chemie, , vol. 500, p. 42,45
反应条件
hydrogenchloride 0.5 h; Yield given;
参考文献
Heterocycles, , vol. 28, # 1 p. 175 - 182
反应条件
1: With potassium phtalimide 2: With hydrazine
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4694 - 4720
反应条件
trichlorophosphate in acetonitrile 0.25 h; Heatinglabelling experiments; MechanismProduct distribution;
参考文献
Heterocycles, , vol. 28, # 1 p. 175 - 182
反应条件
sodium cyanoborohydride; acetic acid in methanol
1 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/21682 A1, 2007 ;
Location in patent: Page/Page column 25-26 ;
反应条件
triethylamine in tetrahydrofuran
T=20°C; 0.5 h;
参考文献
Baggett, Andrew W.; Cournia, Zoe; Han, Min Suk; Patargias, George; Glass, Adam C.; Liu, Shih-Yuan; Nolen, Brad J.
ChemMedChem, 2012 , vol. 7, # 7 p. 1286 - 1294
反应条件
1: With sodium tetrahydroborate in methanol
T=0°C;
2: With hydrogenchloride in water
参考文献
Bajwa, Joginder S.; Parker, David John; Slade, Joel
Patent: US2009/187029 A1, 2009 ;
Location in patent: Page/Page column 13-14 ;