(7S)-7-氨基-1,2,3-三甲氧基-10-甲硫基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮合成路线 （共 15 条）
反应条件
1: 79.5 percent / Na2CO3 / diethyl ether / 5 h / Ambient temperature
2: 89.6 percent / K2CO3 / acetone / 240 h / Ambient temperature
3: 83.5 percent / K2CO3 / acetone / 24 h / Heating
View Scheme
参考文献
Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208
反应条件
in dichloromethane
T=0 - 20°C; 1.75 h;
参考文献
Quinn, Frank R.; Beisler, John A.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 251 - 256
反应条件
1: 79.5 percent / Na2CO3 / diethyl ether / 5 h / Ambient temperature
2: 89.6 percent / K2CO3 / acetone / 240 h / Ambient temperature
View Scheme
参考文献
Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208
反应条件
pyridine in dichloromethane
1 h; Ambient temperature;
参考文献
Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208
反应条件
pyridine in dichloromethane
1 h; Ambient temperature;
参考文献
Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208
